Biomaterials

Goals of this action are interdisciplinary in fields of physics, chemistry and biology:

• (1) To characterise at the nanometer scale, by nano- ion beams, biomimetism and bioactivity processes (formation and growth of biological apatites) at interfaces between bioceramics and living tissues;

• (2) To define experimental strategies to obtain chemical maps at the nanometer scale & local quantitative measurements ; detection of relevant bone trace elements in bioceramics and in bone

• (3) To develop by soft chemistry nanostructured bioactive glasses used as bone substitutes or as scaffolds for tissue engineering;

• (4) To study the influence of porosity and composition (doping in trace elements or in proteins) of these materials on their bioactive properties and on cellular reactions;

• (5) To study by nano-ion beams the distribution of proteins in bioceramics and the behavior of bone cells in contact with bioceramics.(1) To characterise at the nanometer scale, by nano- ion beams, biomimetism and bioactivity processes (formation and growth of biological apatites) at interfaces between bioceramics and living tissues;